Asian Journal of Research in Chemistry

Saroj Nehra ¹, J. B. Dahiya ¹, Sunil Kumar ²

Affiliations
1 Department of Chemistry, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana, IN
2 Thapar Centre for Industrial Research and Development, Paper Mill Campus, Yamuna Nagar- 135001, Haryana, IN

Abstract

The cotton fabric was coated with flame retardant intumescent formulations containing different nanoclays (kaolin, bentonite, nanomer 1.34TCN, nanomer 1.28E) using K-control coater. The thermal behavior of samples was studied using thermogravimetry (TG) and differential scanning calorimetry (DSC). The flame retardant properties were studied using auto flammability test and limiting oxygen index (LOI) to study the effect of different nanoclays with intumescent formulation on cotton fabric. The thermal analysis shows that the onset decomposition temperature of the coated cotton fabric is lowered whereas the temperature at mid of the decomposition is increased on coating. Thermal stability of coated samples is increased after 300 0C, the rate of weight loss is reduced and char yield is increased in comparison to pure cotton fabric. A significant reduction in flame spread time in auto flammability test is observed on inclusion of nanoclays into intumescent system coated onto the cotton fabric. LOI value for pure cotton fabric is increased from 18 % to significant values in the range 27.5-28.5 % on coating fabric with intumescent system containing nanoclays.

Keywords

Cotton Fabric, Flame Retardant, Intumescent, Nanoclay, Thermogravimetry, Flammability

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Sunil Kumar ¹, Surrinder Koul ², Ajay Kumar Meena ³, A. K. Saxena ⁴, O. P. Suri ⁵, K. L. Dhar ⁵

Affiliations
1 Department of Pharmaceutical Chemistry, I. S. F. College of Pharmacy, Moga, 142 001,, IN
2 Department of Bio-organic Chemistry, IIIM, Jammu Tawi 180001, IN
3 National Institute of Ayurvedic Pharmaceutical Research, Moti Bagh Road, Patiala, IN
4 Division of Pharmacology, IIIM, Jammu Tawi, 180001, IN
5 Department of Pharmaceutical Chemistry, I. S. F. College of Pharmacy, Moga, 142 001, IN

Abstract

Plants, source of various bioactive compounds have played crucial role in development of several clinically useful anticancer agents' viz., vincristin, vinblastin, camptothecin derivatives and taxol. Combretastatin, a potent anticancer molecule was first isolated from plant. In this continuation a series of combretastatin analogues has been synthesized on the basis of our butterfly model with two wings as aryl groups and connecting carbon chain as the body. In present study we have synthesized combretastatin analogues of different substitutions, showed potent anticancer activity against different cell lines in different fashion according to substitution. Compound 6 showed marked anticancer activity against colo-205 cell lines (colon cancer).

Keywords

Combretastatin, Antitumor, Phenyl Acetic Acid, Tubulin Inhibitor.

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M. Yadav ¹, Sushil Kumar ¹, Abu Nasar ², Sunil Kumar ²

Affiliations
1 Department of Applied Chemistry, ISM University, Dhanbad, IN
2 Department of Chemistry, S.N. PG College, Azamgarh, IN

Abstract

In the present investigation 4-amino-3-phenyl-5-mercapto-1, 2, 4-triazole has been synthesized and studied as inhibitor for the corrosion of copper in 3.5 % NaCl solution. The inhibition efficiency of the compound have been evaluated by weight loss and electrochemical methods (Impedance spectroscopy and polarization curves). The surface study was done by using SEM techniques. The inhibitor appears to inhibit corrosion process through formation of protective film which was found to consist of Cu(I)-inhibitor complex, cuprous chloride, CuCl or CuCl₂^- complex ion or both on the surface.

Keywords

Copper, Corrosion Inhibition, 3.5% NaCl Solution.

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Susheel Kumar Sindhu ¹, Sunil Kumar ¹, L. R. Singh ²

Affiliations
1 Department of Chemistry, S.S.V. Post Graduate College, Hapur, IN
2 Department of Chemistry, B.S.A. College, Mathura (U.P.), IN

Abstract

A PVC membrane based nickel (II) selective electrode was constructed using 11,14-diaza-4,7-dioxo-2(3),8(9)-dibenzoyl-cyclotetradeca-10,14(1)-diene (DADOCTD) as a neutral carrier. The sensor exhibits a Nernstian response for Ni (II) ions over a wide concentration range of 3.9×10^-6-1.0×10^-1 with a slope of 29.0 mV/decade. It has a relatively fast response time and can be used for 120 days without any considerable divergence in potentials. The proposed sensor revealed relatively good selectively and high sensitivity for Ni (II) over a bi-, tri- and tetravalent metal ions and could be used in a pH range of 3-8. It was successfully also used as an indicator electrode in potentiometer titration and in analysis of concentration of nickel in real samples.

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Anil Kumar Teotia ¹, Sunil Kumar ²

Affiliations
1 Chemistry Division, LNJN, National Institute of Criminology and Forensic Science, Sector-3, Rohini, Delhi-110085, IN
2 Department of Chemistry, Guru Jumbheshwar University, Hisar, IN

Abstract

Various methods were used by forensic chemists for analysis of cannabis. The methods used were depends on the availability of the literature and equipments in the laboratory. This article is a review of the methodology generally used in various forensic laboratories. This article will help forensic chemist in the rapid examination of cannabis.

Keywords

THC, Hashish, Cannabis.

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